Profhilo vs Rejuran: How to Combine for Full-Face Skin Rejuvenation

Skin boosters have become a popular way to treat aging, dullness, and texture loss without changing how your face looks. Two standout options are Profhilo and Rejuran. While they work differently, combining them can produce powerful results. 

Instead of choosing one, more people are now using both to get smoother, firmer, and more even skin. This approach is called a Profhilo and Rejuran combo, and it supports full-face rejuvenation by targeting both hydration and repair.

Let’s Get Straight To The Point

Profhilo and Rejuran can be used together to treat different skin concerns simultaneously. Profhilo hydrates and tightens, while Rejuran repairs and calms. 

Combined, they create a balanced, full-face result that improves texture, tone, and elasticity. It’s a dual skin booster treatment that supports long-term skin health and glow without adding volume or needing downtime.

What Profhilo Does for the Skin

Profhilo is made from pure hyaluronic acid. It’s not a filler and doesn’t add shape or volume. Instead, it spreads evenly beneath the skin and draws in water, hydrating from deep within.

Profhilo’s main benefits:

• Boosts hydration
• Firms loose or crepey skin
• Improves skin elasticity
• Stimulates collagen production

It’s ideal for dry, ageing skin that needs a hydration reset. It is perfect for the cheeks, lower face, and neck.

This makes it a top pick in any complete skin glow treatment.

What Rejuran Does for the Skin

Rejuran is based on polynucleotides, DNA fragments that help skin repair and regenerate. It’s often described as a healing treatment, helping damaged or ageing skin regain strength.

Rejuran’s main benefits:

• Repair damaged skin cells
• Reduces redness and inflammation
• Smooths texture and refines pores
• Improves skin resilience

People often choose Rejuran for concerns like acne scarring, sensitive skin, and dullness. It’s a smart choice for areas with rough texture or visible pores.

It plays a key role in any skin booster rejuvenation plan.

Profhilo vs Rejuran: What’s the Real Difference

While both are injectables and support skin health, they work very differently.

Profhilo hydrates and firms by holding moisture in the skin and triggering collagen. It is best for loose, dry, or dull skin.

Rejuran Repairs and soothes by promoting cell renewal. It is best for skin with uneven texture, post-acne marks, or redness.

You don’t have to choose just one. Using Profhilo and Rejuran together gives a more complete skin result.

When and How to Combine Skin Boosters

Timing matters when it comes to combining skin boosters like Profhilo and Rejuran.

Here are common approaches:

• Start with Profhilo to rehydrate the skin
• Follow up with Rejuran 2–4 weeks later to repair and strengthen
• Or alternate the two months for two to three months

This phased plan allows each product to do its job properly while supporting the others. Over a few weeks, you’re addressing multiple layers of the skin.

Best Areas for Each Treatment

Not all areas of the face respond the same way. Choosing the proper zones for each product can improve results.

Profhilo is best for:

• Cheeks
• Jawline
• Neck
• Lower face
• Areas with dryness or sagging

Rejuran is best for:

• Forehead
• Under-eyes
• Nose
• Areas with redness or acne scars

This makes them the best injectable mix for skin that needs support and smoothing.

What Results Can You Expect

Results won’t happen overnight, but they will build up steadily.

With consistent treatment, people often notice:

• Smoother texture
• Stronger skin barrier
• Brighter skin tone
• Less visible fine lines
• Smaller pores

Most reports see visible changes by the second month. The full effects of each product are shown after 2 to 3 sessions.

This is why many call it the dual skin booster treatment for natural, glowing skin.

Can You Use Profhilo and Rejuran on the Same Day?

Technically, yes. But it’s more common to space them out for better absorption.

Doing both in one session may increase sensitivity, especially for people with reactive skin. Most clinics suggest alternating every two weeks or focusing on different zones if done together.

This approach allows both products to work without overwhelming the skin.

Who Should Consider This Combo Approach

The Profhilo and Rejuran combo is ideal for:

• People over 30 are noticing dullness or skin changes
• Those with sensitive or scarred skin
• Anyone wanting a refreshed look without changing facial structure
• Those looking to prevent early ageing

It’s a preventive and corrective option that suits different skin types and tones.

What to Do Before and After Your Sessions

Good preparation and aftercare make a difference.

Before your treatment:

• Avoid alcohol and anti-inflammatory medicine
• Don’t use harsh skincare for 2–3 days
• Stay hydrated

After your treatment:

• Avoid makeup for 12 hours
• Skip heavy workouts or saunas for 24–48 hours
• Use calming, non-active skincare
• Apply SPF daily

These steps help reduce swelling and allow the injectables to settle correctly.

Why This Injectable Combo Skin Therapy Works So Well

There’s no single product that can do it all. That’s why combining skin boosters works so well.

Each one supports a different layer of skin health:

• Hydration from Profhilo
• Repair from Rejuran
• Stimulation of collagen from both

This full approach results in a clearer, healthier appearance that improves over time. It’s not a one-off solution; it’s part of a smart skincare journey.

Skin boosters like Profhilo and Rejuran are not just trends. They’re reliable, proven options for people who want real results without significant procedures. 

Each offers unique benefits when used alone. When combined, they become a powerful injectable combo skin therapy. 

Whether you’re just starting to notice changes or want to treat specific issues, combining Profhilo and Rejuran gives your skin the best chance to hydrate, heal, and glow. It’s not about changing your face. It’s about giving your skin what it needs to look and feel its best.