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You’ve probably heard about Profhilo or Rejuran. They’re being dubbed the ‘injectable moisturisers‘ of the future — skin boosters that don’t just sit on the surface but work from within. These injectable treatments represent a major leap in the arena of biostimulators and anti-ageing collagen boosting treatments.
These two bio-remodelling injectable treatments are popular choices for good reason. They’re not just cosmetic — they’re medical procedures that support skin regeneration, collagen formation, and long-term skin health.
For those with aging-related skin concerns, acne scar treatment needs, or who simply want firmer skin and smoother texture, both Rejuran and Profhilo deliver — with different strengths.
A revolutionary tissue bioremodeller. Cutting-edge technology delivering natural results. This revolutionary treatment is great for combating the ageing process as it stimulates the production of collagen and elastin, resulting in increased elasticity and support.
Rejuran (often referred to as Rejuran Healer) is a regenerative injectable derived from salmon DNA extract — specifically polynucleotides that promote cellular repair and skin regeneration. This family of polynucleotides includes DNA fragments that help heal damaged skin, stimulate collagen production, and restore skin barrier function.
Rejuran is widely used for treating acne-scarred skin, aging-related skin concerns, and environmental damage. Think of it as your skin’s internal repair agent — a bio-remodelling agent that heals from the cellular level outwards.
Request a consultation
To receive a free private consultation, simply fill out the online enquiry form. Let us know what procedure(s) you are considering and we will get back to you with a time and day to suit.
Why Choose Rejuran?
Here’s why Rejuran is one of the most popular options at aesthetic clinics:
Clients dealing with collagen depletion, loose skin, or visible signs of
sun damage are excellent candidates for Rejuran treatments.
Rejuran Protocol
The Rejuran protocol is precise and tailored for maximal collagen remodelling:
You may experience mosquito-bite-like bumps for the first 6–24 hours after injections.
Aesthetic practitioners often use numbing cream to minimise discomfort during the treatment session.
Profhilo is a non-surgical cosmetic treatment that is different from traditional
volumising procedures. It is placed in specific points just under the surface of the skin
using a fine delivery technique. Rather than adding volume, the treatment is designed
to improve overall skin quality and hydration.
As with all cosmetic procedures, individual experiences can vary. Some people may notice
visible changes in their skin’s appearance, while others may find the effect more subtle.
The treatment plan, expected outcomes, and suitability are best discussed during a
one-on-one consultation with a qualified health professional.
Benefits of Profhilo
Profhilo targets multiple aspects of skin health at once:
It’s a favourite among clients chasing the glass skin, plump look — with no filler distortion.
Profhilo Protocol
This is where Profhilo stands out:
Profhilo is suitable for clients wanting a medical procedure that delivers
visible, subtle improvements in skin hydration and skin quality
improvements without changing their natural look.
Treatment Areas
Rejuran injections can be used across a variety of areas:
Profhilo injections are typically used on:
Due to its fluid spread, Profhilo is not suited to under-eye or highly mobile areas.
Main Differences
| Feature | Rejuran Healer | Profhilo |
|---|---|---|
| Key Ingredient | Polynucleotides (salmon sperm DNA extract) | Blend of high & low molecular weight HA |
| Primary Effects | Skin repair, collagen synthesis, and skin healing | Deep hydration, collagen formation, and skin glow |
| Injection Technique | Micro-injections or injector gun | BAP (Bio Aesthetic Points) manual injection |
| Sessions Required | 2–4 Rejuran sessions | 1–2 sessions |
| Best For | Damaged, sensitive, acne-prone, aging skin | Dry skin, dull skin, skin laxity, aging |
| Downtime | Mild swelling, slight redness (12–36 hrs) | Minimal downtime (2–10 hrs) |
| Treatment Plan | Every 3–6 months | Every 6–12 months |
They’re both injectable moisturisers — but think of Rejuran as the repair serum,
and Profhilo as the hydrating plumper.
Here’s my honest take after treating hundreds of clients with both:
Still unsure? I often combine both — Profhilo for deep hydration and structure,
and Rejuran for barrier repair and texture smoothing.
Yes, they can play nicely together (with the right treatment spacing).
Results & Longevity
Rejuran results are subtle but cumulative — think of it as a
long-term investment in your skin health. You’ll notice
smoother texture and calmness within weeks, but
optimal results appear after 3+ sessions.
Profhilo gives faster gratification — many clients see
glow and plumpness within days of their second treatment.
Results typically last 6 months, though some report
benefits beyond that with maintenance.
Both are considered very safe when administered correctly, but here’s what to expect:
Rejuran Side Effects:
Profhilo Side Effects:
Pro Tip: No actives (like retinol or AHAs) for at least 3–5 days post-treatment.
Let your skin chill and repair.
Request a consultation
To receive a free private consultation, simply fill out the online enquiry form. Let us know what procedure(s) you are considering and we will get back to you with a time and day to suit.
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